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EURO EUS MEETING
Year : 2014  |  Volume : 3  |  Issue : 5  |  Page : 6

Role of high resolution ultrasonography/endoscopic ultrasonography and elastography in predicting lymph node malignancy


1 Cairo University, Cairo, Egypt
2 Assiut University, Cairo, Egypt

Date of Web Publication27-Mar-2014

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Source of Support: None, Conflict of Interest: None


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How to cite this article:
Okasha H, Naguib M, Ezzat R. Role of high resolution ultrasonography/endoscopic ultrasonography and elastography in predicting lymph node malignancy. Endosc Ultrasound 2014;3, Suppl S1:6

How to cite this URL:
Okasha H, Naguib M, Ezzat R. Role of high resolution ultrasonography/endoscopic ultrasonography and elastography in predicting lymph node malignancy. Endosc Ultrasound [serial online] 2014 [cited 2020 Sep 19];3, Suppl S1:6. Available from: http://www.eusjournal.com/text.asp?2014/3/5/6/129493

Objective: To evaluate the role of high resolution ultrasonography (US) and endoscopic ultrasonography (EUS)-elastography in predicting malignant lymphadenopathy.

Methods: This prospective study included 88 patients who underwent EUS or US examination of different groups of lymph nodes (LNs). The classification as benign or malignant based on the real-time elastography pattern and the B-mode US/EUS images was compared to the final diagnosis obtained by EUS or US guided fine-needle aspiration cytology (FNAC), Tru-Cut biopsy or excisional biopsy and follow-up in benign lesions not indicated for biopsy for at least 12 months.

Results: Regarding the echogenicity, 98.3% of the benign LNs were hyperechoic, 1.7% were hypoechoic, while 89.7% of the malignant LNs were hypoechoic, 3.4% were heterogenous and 6.9% were hyperechoic. With cut-off value of 1.93, the sensitivity of longitudinal to transverse ratio was 73% and the specificity was 100%. Score 1 elastography had specificity of 100% in diagnosis of benign LNs, sensitivity was 76.3%, positive predictive value (PPV) was 100%, negative predictive value (NPV) was 84.7% while Score 2 had a sensitivity of 60%, specificity of 31.5%, PPV of 15.3%, NPV of 79.3%. Score 3 had a sensitivity of 70.2%, specificity of 100%, PPV of 13.8%, NPV of 100% in detecting malignancy while Score 4 had a sensitivity of 85.5%, specificity of 100%, PPV of 100%, NPV of 65.5%.

Conclusion: Elastography is a promising diagnostic modality that may complement standard ultrasound and EUS and help guide FNAC during staging of LNs.

Status of the presenting author: Chief resident

The authors declare: No significant relationship.




 

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