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EURO EUS MEETING
Year : 2014  |  Volume : 3  |  Issue : 5  |  Page : 9

Combined endoscopic ultrasonography and endobronchial ultrasound-fine-needle aspiration for evaluation of mediastinal lymph nodes


1 Department of Gastroenterology, Digestive Endoscopy Unit, Mont-Godinne University Hospital, Université Catholique de Louvain, Yvoir, Belgium
2 Department of Pneumology, Mont-Godinne University Hospital, Université Catholique de Louvain, Yvoir, Belgium
3 Department of Pathology, Mont-Godinne University Hospital, Université Catholique de Louvain, Yvoir, Belgium
4 Department of Gastroenterology, Digestive Endoscopy Unit, St-Luc University Hospital, Université Catholique de Louvain, Brussels, Belgium
5 Department of Vascular and Thoracic Surgery, Mont-Godinne University Hospital, Université Catholique de Louvain, Yvoir, Belgium

Date of Web Publication27-Mar-2014

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Source of Support: None, Conflict of Interest: None


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How to cite this article:
Badaoui A, Dahlqvist C, Rahier J F, Weynand B, Ocak S, Deprez P H, Eucher P, Duplaquet F. Combined endoscopic ultrasonography and endobronchial ultrasound-fine-needle aspiration for evaluation of mediastinal lymph nodes. Endosc Ultrasound 2014;3, Suppl S1:9

How to cite this URL:
Badaoui A, Dahlqvist C, Rahier J F, Weynand B, Ocak S, Deprez P H, Eucher P, Duplaquet F. Combined endoscopic ultrasonography and endobronchial ultrasound-fine-needle aspiration for evaluation of mediastinal lymph nodes. Endosc Ultrasound [serial online] 2014 [cited 2020 Sep 29];3, Suppl S1:9. Available from: http://www.eusjournal.com/text.asp?2014/3/5/9/129510

Objectives: Endoscopic ultrasonography (EUS) and endobronchial ultrasound-fine-needle aspiration (EBUS-FNA), is an accurate technique for evaluation of mediastinal lymph nodes (MLN) and stadification of lung cancer. The aims of the study are to evaluate the feasibility and the efficacy of the combined technique compared with mediastinoscopy for the diagnosis of MLN.

Design and Methods: All patients with suspected malignant MLN and/or lung lesion identified by positron emission tomography-computed tomography underwent combined EUS-EBUS-FNA. The combined procedure was performed in outpatients under general anesthesia for EUS and sedation by intravenous midazolam for EBUS when performed separately, using linear-array echoendoscopes. The MLN were punctured during the EUS and EBUS-FNA procedures with a 22 gauge needle.

Results: Thirty-four patients underwent consecutively EUS and EBUS-FNA between September 2011 and November 2013 (8 women, 26 men, mean age of 65.9 year, range: 51-83). Combined EUS-EBUS-FNA was performed in a single time procedure in 26 patients (mean time 50 min) and in two different times in eight patients (mean delay 3 days). Twenty-five malignant and 9 inflammatory lesions were diagnosed. Mediastinoscopy was performed in nine patients and confirmed in eight patients the initial combined EUS-EBUS-FNA diagnosis. The diagnosis was obtained in 91.2% with EUS-FNA, 70.6% with EBUS-FNA and 97% when combined procedure was performed. The overall sensitivity, specificity, positive and negative predictive values of EUS-EBUS-FNA for diagnosing malignancy were 96.5%, 100%, 100% and 90% respectively. No complications related to the procedure were observed.

Conclusion: Combined EUS-EBUS-FNA represents an accurate technique in the diagnosis of MLN, can be done in a single time procedure and has the advantage of being less invasive than mediastinoscopy.

Status of the presenting author: Chief resident

The authors declare: No significant relationship.




 

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