• Users Online:1224
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Year : 2017  |  Volume : 6  |  Issue : 7  |  Page : 28

Endoscopic ultrasound-guided versus percutaneous versus endoscopic retrograde cholangiopancreatography biliary drainage in patients with malignant biliary obstruction: A case–controlled study from a large referral center

Chulalongkorn University, Bangkok, Thailand

Correspondence Address:
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2303-9027.212321

Rights and Permissions

Background: Endoscopic retrograde cholangiopancreatography (ERCP) with transpapillary stenting is the first-line biliary drainage in patients with malignant biliary obstruction (MBO). Percutaneous transhepatic biliary drainage (PTBD) and EUS-guided biliary drainage (EUS-BD) are alternative methods. Objectives: To compare efficacy and safety of these three methods as a case–controlled study. Methods: From January 2014 to September 2016, 144 patients were followed for their clinical recurrent biliary obstruction (RBO) or their death or 1-year follow-up. Results: EUS-BD, PTBD, and ERCP were performed in 30, 60, and 54 patients, respectively. Technical success rate (TSR) of EUS-BD was significantly lower than both PTBD and ERCP (84% vs. 100% and 100%, respectively, P < 0.001). PTBD had significantly lower clinical success rate (CSR) than ERCP (65% vs. 85%, respectively, P < 0.001). RBO rates of PTBD were significantly higher than those of EUS-BD and ERCP (52% vs. 17% vs. 13%, respectively, P < 0.001). The survival analysis is not statistically significant among the three methods (P = 0.07, log-rank test). Conclusions: In patients with MBO, ERCP with transpapillary drainage should be selected as the first choice because ERCP provided the high TSR and CSR. EUS-BD and PTBD should be selected as the next alternatives because EUS-BD provided lower TSR and PTBD had lower CSR and higher RBO.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded31    
    Comments [Add]    

Recommend this journal