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ABSTRACT
Year : 2017  |  Volume : 6  |  Issue : 8  |  Page : 56

Stimulated Raman microscopy and endoscopy: A route toward real-time intraoperative histology?


Institut Fresnel CNRS Aix Marseille Univ, Mosaic, Marseille, France

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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2303-9027.218434

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We present advances in multiphoton and coherent Raman microscopy and endoscopy for gastrointestinal cancer detection. We use stimulated Raman scattering combined with second harmonic generation to reveal cell nuclei, cytoplasm, and collagen simultaneously in human tissues. For the first time, cell nuclei, cytoplasm, and extracellular matrix can be visualized in real time with image quality similar to histology.


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