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EDITORIAL
Year : 2017  |  Volume : 6  |  Issue : 9  |  Page : 57

Re-defining the role of EUS in pancreatic adenocarcinoma in 2017


Pancreato-Biliary Endoscopy and Endosonography Division, Pancreas Translational and Clinical Research Center, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy

Date of Submission12-Jul-2017
Date of Acceptance31-Aug-2017
Date of Web Publication29-Dec-2017

Correspondence Address:
Dr. Paolo G Arcidiacono
Pancreato-Biliary Endoscopy and Endosonography Division, Pancreas Translational and Clinical Research Center, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan
Italy
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/eus.eus_59_17

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How to cite this article:
Arcidiacono PG. Re-defining the role of EUS in pancreatic adenocarcinoma in 2017. Endosc Ultrasound 2017;6, Suppl S3:57

How to cite this URL:
Arcidiacono PG. Re-defining the role of EUS in pancreatic adenocarcinoma in 2017. Endosc Ultrasound [serial online] 2017 [cited 2018 Jul 20];6, Suppl S3:57. Available from: http://www.eusjournal.com/text.asp?2017/6/9/57/221928



Pancreatic ductal adenocarcinoma (PDAC) is a very severe disease, considered in the recent years to be the fifth malignancy in the Western Countries.

Among those, PDAC is the most aggressive being the fourth cause of death; furthermore, its incidence is constantly growing over time, and in a recent report, its estimated increase in the next decade will lead this tumor to become the first malignancy.

Unfortunately, regardless big and constant improvement in the diagnostic cross-sectional modalities, the scarcity of symptoms specifically related to the disease delays the diagnosis, and for this, only 9% of lesions are localized and >50% have distant metastasis.[1],[2],[3]

Even if the patient has a lesion deemed to be resectable at the time of the diagnosis, the survival rate at 5 years is still <20% being nearly 40% in most favorable cases for surgical treatment (Stage 1a lesions).[4]

In the recent years, the development of endoscopic ultrasonography (EUS) has led to an increase of diagnostic capabilities also in the presence of patients with clinical suspicion of pancreatic cancer negative at the standard diagnostic algorithm. This procedure has improved the detection rates of small pancreatic lesions and the differential diagnosis of benign/malignant tumor with an impact on therapeutic strategies.

This special issue of endoscopic ultrasound reported a series of articles that are considering diagnostic and therapeutic open questions in PDAC with a particular focus on the role of EUS in this regard.

These papers are the result of the lecture and debate sessions that took place in the recent 14th EURO-EUS Meeting held in Milan and are the first of a series of special issues that will give a comprehensive overview of pancreatic solid and cystic lesions.



 
  References Top

1.
Altekruse S, Kosary C, Krapcho M, et al. “SEER Cancer Statistics Review,” National Cancer Institute.  Back to cited text no. 1
    
2.
Globocan. GLOBOCAN 2012 v1.0: Estimated cancer incidence, mortality and prevalence worldwide in 2012. International Agency for Research on Cancer 2012.  Back to cited text no. 2
    
3.
The Surveillance E, and End Results (SEER) Program of the National Cancer Institute. Cancer Stat Facts: Pancreas Cancer. Available online: https://seer.cancer.gov/statfacts/html/pancreas.html  Back to cited text no. 3
    
4.
Franko J, Hugec V, Lopes TL, et al. Survival among pancreaticoduodenectomy patients treated for pancreatic head cancer <1 or 2 cm. Ann Surg Oncol 2013;20:357-61. doi: 10.1245/s10434-012-2621-y. Epub 2012 Sep 1. PubMed PMID: 22941171.  Back to cited text no. 4
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