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Year : 2018  |  Volume : 7  |  Issue : 6  |  Page : 383-388

Initial experience with EUS-guided microbiopsy forceps in diagnosing pancreatic cystic lesions: A multicenter feasibility study (with video)

1 Division of Endoscopy, Gastro Unit, Copenhagen University Hospital Herlev, Copenhagen, Denmark
2 Division of Endoscopy, Gastro Unit, Copenhagen University Hospital Herlev; Department of Gastrointestinal Surgery, Slagelse Hospital, Slagelse, Denmark
3 Department of Medicine, Haukeland University Hospital, Bergen, Norway
4 Department of Hepato-Gastroenterology, Institut Paoli Calmettes, Marseille, France
5 Pancreato-Biliary Endoscopy and Endosonography Division, San Raffaele Scientific Institute, Milan, Italy
6 Department of Gastroenterology and Liver Diseases, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
7 Endoscopy Unit, Gastroenterology Division, University Hospital Ramon Y Cajal, Madrid, Spain
8 Department of Pathology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
9 Department of Pathology, Copenhagen University Hospital Herlev, Herlev, Denmark
10 Department of Gastrointestinal Surgery, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark

Correspondence Address:
Dr. Bojan Kovacevic
Division of Endoscopy, Gastro Unit, Copenhagen University Hospital Herlev, Herlev Ringvej 75, Dk-2730 Herlev
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/eus.eus_16_18

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Background and Objectives: Cystic lesions of the pancreas represent a diagnostic dilemma. Recently, a through-the-needle microbiopsy forceps has become available, enabling procurement of EUS-guided histological specimens from the pancreatic cyst wall. The aim of this study was to evaluate the use of this novel instrument in a multicenter clinical setting. Patients and Methods: Patients referred for EUS evaluation of pancreatic cysts and attempted EUS-guided microbiopsy was included retrospectively from six international tertiary centers. Patient's demographics, EUS findings, technical and clinical success, and histopathological results were recorded. Results: A total of 28 patients were identified. We report a technical success rate of 85.7% (n = 24). Biopsies were generally of good quality and contributed to the diagnosis in 20 patients (clinical success of 71.4%). Three adverse events were recorded (10.7%). Conclusions: The use of the microbiopsy forceps is feasible with acceptable rates of technical and clinical success. Prospective studies are warranted to determine the diagnostic potential compared to the other modalities. However, the results from this preliminary study are promising.

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