Endoscopic Ultrasound

ORIGINAL ARTICLE
Year
: 2019  |  Volume : 8  |  Issue : 3  |  Page : 204--208

Endobronchial ultrasound-guided transbronchial needle aspiration under general anesthesia versus bronchoscopist-directed deep sedation: A retrospective analysis


Christian G Cornelissen, Johanna Dapper, Michael Dreher, Tobias Müller 
 Department of Pneumology and Intensive Care Medicine, University Hospital RWTH Aachen, Aachen, Germany

Correspondence Address:
Dr. Tobias Müller
Department of Pneumology and Intensive Care Medicine, University Hospital RWTH Aachen, Pauwelsstrasse 30, Aachen 52074
Germany

Background: Different sedation strategies are used during endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for the diagnostic workup of lung cancer including general anesthesia (GA) and moderate sedation. However, no data are available about EBUS-TBNA under deep sedation (DS) with fiberoptic intubation directed by the investigator. Materials and Methods: A retrospective analysis of EBUS-TBNAs under GA (n = 160) or DS (n = 105) was performed. Results: Unadjusted diagnostic yield did not differ significantly between the groups (GA: 42.5% vs. DS: 53.3%P= 0.1018). Similar results were obtained when only patients with a final diagnosis of malignancy were analyzed (GA: 53.6% vs. DS: 61.5%P= 0.2675). Adverse events (AEs) occurred more often under DS (GA: 27.5% vs. DS: 59.1%P< 0.0001) due to more sedation-related problems whereas severe AEs tended to be higher under GA (GA: 7.5% vs. DS: 1.9%P= 0.0523). Conclusion: In summary, our data show that the diagnostic yield and the complication rate of EBUS-TBNA performed under DS are similar compared to GA. Hence, in an appropriate setting, EBUS-TBNA can be performed safely under DS.


How to cite this article:
Cornelissen CG, Dapper J, Dreher M, Müller T. Endobronchial ultrasound-guided transbronchial needle aspiration under general anesthesia versus bronchoscopist-directed deep sedation: A retrospective analysis.Endosc Ultrasound 2019;8:204-208


How to cite this URL:
Cornelissen CG, Dapper J, Dreher M, Müller T. Endobronchial ultrasound-guided transbronchial needle aspiration under general anesthesia versus bronchoscopist-directed deep sedation: A retrospective analysis. Endosc Ultrasound [serial online] 2019 [cited 2019 Nov 12 ];8:204-208
Available from: http://www.eusjournal.com/article.asp?issn=2303-9027;year=2019;volume=8;issue=3;spage=204;epage=208;aulast=Cornelissen;type=0