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REVIEW ARTICLE
Year : 2017  |  Volume : 6  |  Issue : 6  |  Page : 376-381

Can endoscopic ultrasound-guided needle-based confocal laser endomicroscopy replace fine-needle aspiration for pancreatic and mediastinal diseases?


1 Endoscopy Center, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China
2 Department of Gastroenterology, Hepatology and Nutrition-Unit1466, UT MD Anderson Cancer Center, Houston, Texas, USA
3 Endoscopy Center, Institute Paoli-Calmettes, Marseille, France
4 Department of Gastroenterology, Changhai Hospital, Navy Medical University, Shanghai, China
5 Division of Gastroenterology, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing, China
6 Department of Gastroenterology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China
7 National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Correspondence Address:
Dr. Siyu Sun
The Shengjing Hospital of China Medical University, No. 36, Sanhao Street, Shenyang 110004, Liaoning Province
China
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/eus.eus_87_17

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New applications of confocal laser endomicroscopy (CLE) have been developed, such as needle-based CLE (nCLE) for pancreatic masses, pancreatic cystic tumors, and lymph nodes. nCLE is feasible during endoscopic ultrasound (EUS) examination, and preliminary results are very encouraging and suggest this technology may be used in future as a useful adjunct in cases of inconclusive EUS-guided fine-needle aspiration. The aim of this paper is to give an update in this new technology and to define its place in the diagnosis of pancreatic masses and mediastinal diseases.


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